The 4-star Papadopoli Venezia is in the heart of the Sestiere Santa Croce area. It is a 2-minute walk from the bus terminus of Piazzale Roma, and 293 m from Santa Lucia Train Station. Wi-Fi is free throughout the entire building.

The Hotel Papadopoli Venezia-MGallery Collection features elegantly decorated rooms and suites with romantic views of the Papadopoli Gardens or Tolentini Canal. Each features designer amenities and classic 18th-century Venetian furnishings.

The hotel is complete with a private dock, where guests can arrive directly by boat or water taxi. A concierge service is also available. The staff can arrange boat rides, or book tickets to La Fenice Opera House, museums and exhibitions.

Papadopoli Restaurant serves Venetian cuisine. In the atrium, and filled with tropical plants, it is available for lunch and dinner from the menu. A breakfast buffet is served daily.

The Salotto Veneziano bar is complete with a private library with free daily newspapers. Live music is arranged in the evenings.